Drug and Alcohol Dependence
Volume 108, Issue 1 , Pages 56-64 , 1 April 2010

The effectiveness of a school-based substance abuse prevention program: 18-Month follow-up of the EU-Dap cluster randomized controlled trial

  • Fabrizio Faggiano

      Affiliations

    • Avogadro University, Via Solaroli 17, 28100 Novara, Italy
    • Piedmont Centre for Drug Addiction Epidemiology, Via Sabaudia 164, 10095 Grugliasco, TO, Italy
    • Corresponding Author InformationCorresponding author at: Department of Clinical and Experimental Medicine, Avogadro University, Via Solaroli 17, 28100 Novara, Italy. Tel.: +39 0321 660661/011 40188309; fax: +39 0321 660682.
  • ,
  • Federica Vigna-Taglianti

      Affiliations

    • Avogadro University, Via Solaroli 17, 28100 Novara, Italy
    • Piedmont Centre for Drug Addiction Epidemiology, Via Sabaudia 164, 10095 Grugliasco, TO, Italy
  • ,
  • Gregor Burkhart

      Affiliations

    • EMCDDA, Cais do Sodré, 1249-289 Lisbon, Portugal
  • ,
  • Karl Bohrn

      Affiliations

    • ISG, Linke Wienzelte 112/4, 1060 Wien, Austria
  • ,
  • Luca Cuomo

      Affiliations

    • Piedmont Centre for Drug Addiction Epidemiology, Via Sabaudia 164, 10095 Grugliasco, TO, Italy
  • ,
  • Dario Gregori

      Affiliations

    • University of Turin, Via Santena 5 bis, 10126 Torino, Italy
  • ,
  • Massimiliano Panella

      Affiliations

    • Avogadro University, Via Solaroli 17, 28100 Novara, Italy
  • ,
  • Maria Scatigna

      Affiliations

    • University of L’Aquila – Ospedale San Salvatore, Edificio n.6, Località Coppito, 67010 L’Aquila, Italy
  • ,
  • Roberta Siliquini

      Affiliations

    • University of Turin, Via Santena 5 bis, 10126 Torino, Italy
    • Piedmont Centre for Drug Addiction Epidemiology, Via Sabaudia 164, 10095 Grugliasco, TO, Italy
  • ,
  • Laura Varona

      Affiliations

    • EDEX, Particolar de Indautxu 9, 48011 Bilbao, Spain
  • ,
  • Peer van der Kreeft

      Affiliations

    • Faculty for Social Work and Social Welfare Studies of the University College, Kortrijksesteenweg 14, 9000 Gent, Belgium
  • ,
  • Maro Vassara

      Affiliations

    • Pyxida – Drug Abuse Prevention and Health Promotion Centre, Eptapyrgiou 151, 56626 Thessaloniki, Greece
    • University Mental Health Research Institute 2, Soranou Tou Efessiou, 11527 Athens, Greece
  • ,
  • Gudrun Wiborg

      Affiliations

    • IFT Nord, Düsternbrooker Weg 2, 24105 Kiel, Germany
  • ,
  • Maria Rosaria Galanti

      Affiliations

    • Dept. of Public Health Sciences, Karolinska Institutet – Norrbacka, SE-171 76 Stockholm, Sweden
  • ,
  • the EU-Dap Study Group

      Affiliations

    • EU-Dap Study Group: Roberta Siliquini, Barbara Zunino, Luca Cuomo, Federica Vigna-Taglianti, Serena Vadrucci, Laura Vitale (Piedmont Centre for Drug Addiction Epidemiology – Turin, Italy); Peer van der Kreeft (De Sleutel – Gent, Belgium); Juan Carlos Melero, Laura Varona (EDEX – Bilbao, Spain); Gudrum Wiborg (IFT-Nord – Kiel, Germany); Clive Richardson (University Mental Health Research Institute – Athens, Greece); Maro Vassara (Pyxida – Thessaloniki, Greece); M. Rosaria Galanti, Sara Sanchez and Lotta Jansson (Dept. of Public Health Sciences, Karolinska Institutet – Stockholm, Sweden, formerly of the Stockholm Centre of Public Health); Gregor Burkhart (EMCDDA – Lisbon, Portugal); Fabrizio Faggiano, Massimiliano Panella (Dept of Clinical and Experimental Medicine, Avogadro University – Novara, Italy); Leila Fabiani, Maria Scatigna (Dept of Internal Medicine and Public Health – University of L’Aquila – L’Aquila, Italy).

Received 28 May 2009 ,Revised 16 September 2009 ,Accepted 16 November 2009.

References 

  1. Altman DG. Confidence intervals for the number needed to treat. BMJ. 1998;317:1309–1312
  2. Altman DG. Practical Statistics for Medical Research. London: Chapman and Hall; 1991;
  3. Bauer DJ, Preacher KJ, Gil KM. Conceptualizing and testing random indirect effects and moderated mediation in multilevel models: new procedures and recommendations. Psychological Methods. 2006;11(No. 2):142–163
  4. Bauman KE, Ennett ST, Foshee VA, Pemberton M, Hicks K. Correlates of participation in a family-directed tobacco and alcohol prevention program for adolescents. Health Education & Behaviour. 2001;4:440–461
  5. Botvin GJ, Eng A, Williams CL. Preventing the onset of cigarette smoking through life skills training. Preventive Medicine. 1980;9:135–143
  6. Botvin GJ, Baker E, Filazzola AD, Botvin EM. A cognitive-behavioral approach to substance abuse prevention: one-year follow-up. Addictive Behaviour. 1990;15:47–63
  7. Botvin GJ, Baker E, Dusenbury L, Botvin EM, Diaz T. Long-term follow-up results of a randomized drug abuse prevention trial in a white middle-class population. JAMA. 1995;273:1106–1112
  8. Botvin GJ, Griffin KW, Diaz T, Miller N, Ifill-Williams M. Smoking initiation and escalation in early adolescent girls: one-year follow-up of a school-based prevention intervention for minority youth. Journal of the American Medical Women's Association. 1999;54(139–43):152
  9. Campbell R, Starkey F, Holliday J, Audrey S, Bloor M, Parry-Langdon N, et al. An informal school-based peer-led intervention for smoking prevention in adolescence (ASSIST): a cluster randomised trial. Lancet. 2008;371:1595–1602
  10. Caraballo RS, Giovino GA, Pechacek TF. Self-reported cigarette smoking vs. serum cotinine among U.S. adolescents. Nicotine & Tobacco Research. 2004;6:19–25
  11. Cohen DA, Linton KLP. Parent participation in an adolescent drug abuse prevention program. Journal of Drug Education. 1995;2:159–169
  12. Crone MR, Reijneveld SA, Willemsen MC, van Leerdam FJM, Spruijt RD, Hira Sing RA. Prevention of smoking in adolescents with lower education: a school based intervention study. Journal of Epidemiology and Community Health. 2003;57:675–680
  13. DeWit DJ, Adlaf EM, Offord DR, Ogborne AC. Age at first alcohol use: a risk factor for the development of alcohol disorders. American Journal of Psychiatry. 2000;157(5):745–750
  14. Ellickson PL, Bell RM. Drug prevention in junior high: a multi-site longitudinal test. Science. 1990;247:1299–1305
  15. Ellickson PL, Hays RD, Bell RM. Stepping through the drug use sequenze: longitudinal scalogram analysis of initiation and regular use. Journal of Abnormal Psychology. 1992;101:441–451
  16. Ellickson PL, McCaffrey DF, Ghosh Dastidar B, Longshore DL. New inroads in preventing adolescent drug use: results from a large-scale trial of Project ALERT in middle schools. American Journal of Public Health. 2003;93:1830–1836
  17. EMCDDA . Annual Report 2007: The State of the Drugs Problem in Europe. Lisbon: EMCDDA; 2007;
  18. Evans RI. Smoking in children: developing a social psychological strategy of deterrence. Preventive Medicine. 1976;51:122–127
  19. Ezzati M, Lopez AD. Estimates of global mortality attributable to smoking in 2000. Lancet. 2003;362:847–852
  20. Faggiano F, Vigna-Taglianti FD, Versino E, Zambon A, Borraccino A, Lemma P. School-based prevention for illicit drugs’ use. The Cochrane Database of Systematic Reviews. 2005;(2):Art. No.: CD003020.pub2
  21. Faggiano F, Richardson C, Bohrn K, Galanti MR the EU-Dap Study Group. A cluster randomized controlled trial of school-based prevention of tobacco, alcohol and drugs use: the EU-Dap design and study population. Preventive Medicine. 2007;44:170–173
  22. Faggiano F, Galanti MR, Bohrn K, Burkhart G, Cuomo L, Vigna-Taglianti F, et al. The effectiveness of a school-based substance abuse prevention program: EU-Dap Cluster Randomised Controlled Trial. Preventive Medicine. 2008;47:537–543
  23. Foxcroft DR, Ireland D, Lowe G, Breen R. Primary prevention for alcohol misuse in young people. The Cochrane Database of Systematic Reviews. 2002;(3):Art. No.: CD003024
  24. Galanti MR, Siliquini R, Cuomo L, Melero JC, Perez T, Panella M, et al. Testing anonymous link procedures for follow-up of adolescents in a school-based trial: the EU-Dap pilot study. Preventive Medicine. 2007;44:174–177
  25. Goldstein H. Multilevel Statistical Models. 3rd ed.. London: Edward Arnold; 2003;
  26. Gorman DM. Does measurement dependence explain the effects of Life Skills Training Program on smoking outcomes?. Preventive Medicine. 2005;40:479–487
  27. Gorman DM, Conde E, Huber JC. The creation of evidence in ‘evidence-based’ drug prevention: a critique of the strengthening families program plus life skills training evaluation. Drug Alcohol Review. 2007;26:585–593
  28. Grant BF, Dawson DA. Age at onset of alcohol use and its association with DSM-IV alcohol abuse and dependence: results from the National Longitudinal Alcohol Epidemiologic Survey. Journal of Substance Abuse. 1997;9:103–110
  29. Grant BF, Dawson DA. Age of onset of drug use and its association with DSM-IV drug abuse and dependence: results from the national longitudinal alcohol epidemiologic survey. Journal of Substance Abuse. 1998;10(2):164–173
  30. Griffin KW, Botvin GJ, Nichols TR, Doyle MM. Effectiveness of a Universal Drug Abuse Prevention Approach for Youth at High Risk for Substance Use Initiation. Preventive Medicine. 2003;36:1–7
  31. Hibell B, Andersson B, Bjarnason T, Ahlström S, Balakireva O, Kokkevi A, Morgan M. The ESPAD Report 2003 Alcohol and Other Drug Use Among Students in 35 European Countries. The Swedish Council for Information on Alcohol and Other Drugs, Council of Europe, Pompidou Group. Stockholm, 2004.
  32. Josendal O, Aaro LE, Bergh I. Effects of a school-based smoking prevention program among subgroups of adolescents. Health Education Research. 1998;13:215–224
  33. Kandel D, Chen K, Warner LA, Kessler RC, Grant B. Prevalence and demographic correlates of symptoms of last year dependence on alcohol, nicotine, marijuana and cocaine in the U.S. population. Drug and Alcohol Dependence. 1997;44:11–29
  34. McCambridge J. A case study of publication bias in an influential series of reviews of drug education. Drug and Alcohol Review. 2007;26:463–468
  35. Muller-Riemenschneider F, Bockelbrink A, Reinhold T, Rasch A, Greiner W, Willich SN. Long-term effectiveness of behavioural interventions to prevent smoking among children and youth. Tobacco Control. 2008;17:301–312
  36. Murray DM, Varnell SP, Blitstein JL. Design and analysis of Group-randomized trials: a review of recent methodological developments. American Journal of Public Health. 2004;94:423–432
  37. O’Loughlin J, DiFranza J, Tyndale RF, Meshefedjian G, McMillan-Davey E, Clarke PB, et al. Nicotine-dependence symptoms are associated with smoking frequency in adolescents. American Journal of Preventive Medicine. 2003;25:219–225
  38. Patra J, Taylor B, Rehm JT, Baliunas D, Popova S. Substance-attributable morbidity and mortality changes to Canada's epidemiological profile: measurable differences over a ten-year period. Canadian Journal of Public Health. 2007;98:228–234
  39. Peterson AV, Kealey KA, Mann SL, Marek PM, Sarason IG. Hutchinson Smoking Prevention Project: long-term randomized trial in school-based tobacco use prevention-results on smoking. Journal of the National Cancer Institute. 2000;92:1979–1991
  40. Pitkanen T, Lyyra AL, Pulkkinen L. Age of onset of drinking and the use of alcohol in adulthood: a follow-up study from age 8–42 for females and males. Addiction. 2005;100:652–661
  41. Post A, Gilljam H, Rosendahl I, Meurling L, Bremberg S, Galanti MR. Validity of self-reports in a cohort of Swedish adolescent smokers and smokeless tobacco (snus) users. Tobacco Control. 2005;14:114–117
  42. Rasbash J, Steele F, Browne W, Prosser B. A user's Guide to MLwiN, version 2.0. Centre for Multilevel Modelling. Institute of Education, University of London; 2004;
  43. Rehm J, Sulkowska U, Manczuk M, Boffetta P, Powles J, Popola S, et al. Alcohol accounts for a high proportion of premature mortality in central and eastern Europe. International Journal of Epidemiology. 2007;36:458–467
  44. Scheier LM, Botvin GJ, Griffin KW. Preventive intervention effects on developmental progression in drug use: structural equation modeling analyses using longitudinal data. Prevention Science. 2001;2:91–112
  45. Spoth RL, Redmond C, Trudeau L, Shin C. Longitudinal substance initiation outcomes for a universal preventive intervention combining family and school programs. Psychology of Addictive Behaviour. 2002;16(2):129–134
  46. Spoth R, Redmond C, Shin C, Azevedo K. Brief family intervention effects on adolescent substance initiation: school-level growth curve analyses 6 years following baseline. Journal of Consulting and Clinical Psychology. 2004;72(3):535–542
  47. Stead M, Stradling R, MacNeil M, MacKintosh AM, Minty S. Implementation evaluation of the Blueprint multi-component drug prevention program: fidelity of school component delivery. Drug and Alcohol Review. 2007;26:653–664
  48. Sussman S, Earleywine M, Wills T, Cody C, Biglan T, Dent CW, et al. The motivation, skills, and decision-making model of “drug abuse” prevention. Substance Use & Misuse. 2004;39:1971–2016
  49. Thomas R, Perera R. School-based programmes for preventing smoking. The Cochrane Database of Systematic Reviews. 2006;(3):Art. No.: CD001293
  50. UNICRI . School-based Drug Education: A Guide for Practitioners and the Wider Community. United Nations Office for Drug Control and Crime Prevention; 2003;
  51. van der Kreeft P, Wiborg G, Galanti MR, Siliquini R, Bohrn K, Scatigna M, et al. Unplugged”: a new European school program against substance abuse. Drugs Education Prevention and Policy. 2009;16:167–181
  52. Wood AM, White IR, Hillsdon M, Carpenter J. Comparison of imputation and modelling methods in the analysis of a physical activity trial with missing outcomes. International Journal of Epidemiology. 2005;34:89–99

PII: S0376-8716(09)00438-4

doi: 10.1016/j.drugalcdep.2009.11.018

Drug and Alcohol Dependence
Volume 108, Issue 1 , Pages 56-64 , 1 April 2010