« Previous
Next »
Drug and Alcohol Dependence
Volume 121, Issue 1
, Pages 1-9
, 1 February 2012
MDMA and temperature: A review of the thermal effects of ‘Ecstasy’ in humans
References
- . Effects of ambient temperature on the relative reinforcing strength of MDMA using a choice procedure in monkeys. Psychopharmacology. 2008;196:63–70
- . Recreational ecstasy use: acute effects potentiated by ambient conditions?. Neuropsychobiology. 2006;53:113
- . A new brain area affected by 3,4-methylenedioxymethamphetamine: a microdialysis-biotelemetry study. Eur. J. Pharmacol. 2008;596:84–88
- . Brain hyperthermia induced by MDMA (‘ecstasy’): modulation by environmental conditions. Eur. J. Neurosci. 2004;20:51–58
- . Multiple severe complications from recreational ingestion of MDMA (’Ecstasy’). JAMA. 1987;258:780–781
- . Ecstasy, 3,4-methylenedioxymethamphetamine (MDMA), a fatality associated with coagulopathy and hyperthermia. J. Royal Soc. Med. 1991;84:371
- . Subjective reports on the effects of the MDMA (Ecstasy) experience in humans. Prog. Neuropsychopharmacol. Biol. Psychiatry. 1995;19:1137–1145
- . Heat increases 3,4-methylenedioxymethamphetamine administration and social effects in rats. Eur. J. Pharmacol. 2003;482:339–341
- . A fatal trip with ecstasy: a case of 3,4-methylenedioxymethamphetamine toxicity. J. Royal Soc. Med. 1996;89:51–52
- . Hyperthermia following MDMA administration in rats: effects of ambient temperature, water consumption, and chronic dosing. Physiol. Behav. 1995;58:877–882
- . Ecstasy in recreational users: self-reported psychological and physiological effects. Hum. Psychopharmacol. 1997;12:91–97
- . Pharmacological interactions between 3,4-methylenedioxymethamphetamine (ecstasy) and paroxetine: pharmacological effects and pharmacodynamics. J. Pharmacol. Exp. Ther. 2007;323:954–962
- . Diurnal Variation. Stress and Fatigue in Human Performance. Chichester and New York: Wiley; 1983;
- . Thermoregulatory effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans. Psychopharmacology. 2005;183:248–256
- . Thermophysiological response to hyperthermic drugs: extrapolating from rodent to human. Prog. Brain Res. 2007;162:63–79
- . Effects of 3,4-methylenedioxymethamphetamine on thermoregulatory responses in the rat. Pharmacol. Biochem. Behav. 1991;38:339–344
- . The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”). Pharmacol. Rev. 2003;55:463–508
- . Effect of ambient temperature and a prior neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA) on the hyperthermic response of rats to a single or repeated (‘binge’ ingestion) low dose of MDMA. Psychopharmacology. 2004;173:264–269
- . Epidemiological and clinical characteristics of acute MDMA related presentations to an inner city London Emergency Department. Neuropsychobiology. 2009;60:214
- . Psychobiologic effects of 3,4-methylenedioxymethamphetamine in humans: methodological considerations and preliminary observations. Behav. Brain. Res. 1996;73:103–107
- . Dantrolene in the treatment of MDMA-related hyperpyrexia: a systematic review. CJEM. 2010;12:435–442
- . Acute toxicity of ‘Ecstasy’ (MDMA) and related compounds: overview of pathophysiology and clinical management. Br. J. Anaesth. 2005;96:678–685
- . Morbidity associated with MDMA (ecstasy) abuse—a survey of emergency department admissions. Hum. Exp. Toxicol. 2011;30:259–266
- . Subjective and hormonal effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans. Psychopharmacology. 2002;162:396–405
- . Toxicity and deaths from 3,4-methylenedioxymethamphetamine (“Ecstasy”). Lancet. 1992;340:384–387
- . Causes and consequences of the loss of serotonergic presynapses elicited by the consumption of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) and its congeners. J. Neural Transm. 1997;104:771–794
- . Plasma drug concentrations and physiological measures in dance party participants. Neuropsychopharmacology. 2006;31:424–430
- . Decreased cerebral cortical serotonin transporter binding in ecstasy users: a positron emission tomography/[(11)C]DASB and structural brain imaging study. Brain. 2010;133:1779–1797
- . Brian hyperthermia during physiological and pathological conditions: causes, mechanisms, and functional implications. Curr. Neurovasc. Res. 2004;1:77–90
- . Physiological and subjective responses to 3,4-methylenedioxymethamphetamine administration. J. Clin. Psychopharmacol. 2008;28:432–440
- . Thermoregulatory responses to environmental toxicants: the interactions of thermal stress and toxicant exposure. Toxicol. App. Pharmacol. 2008;233:146–161
- . The serotonin uptake inhibitor citalopram reduces cardiovascular and vegetative effects of 3,4-methylenedioxymethamphetamine (ecstasy) in human volunteers. J. Psychopharmacol. 2000;14:269–274
- . Psychological and physiological effects of MDMA (ecstasy) after pretreatment with the 5-HT2 antagonist ketanserin in healthy humans. Neuropsychopharmacology. 2000;23:396–404
- . Gender differences in the subjective effects of MDMA. Psychopharmacology. 2001;154:161–168
- . Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat. J. Neurosci. 1998;18:5086–5094
- . Cardiovascular and neuroendocrine effects and pharmacokinetics of 3,4-methylenedioxymethamphetamine in humans. J. Pharmacol. Exp. Ther. 1999;290:136–145
- . The role of the sympathetic nervous system and uncoupling proteins in the thermogenesis induced by 3,4-methylenedioxymethamphetamine. J. Mol. Med. 2004;82:787–799
- . The acute psychobiological impacts of ilicit 3,4-methylenedioxymethamphetamine (MDMA, ‘Ecstasy’) consumption in recreational environments. Neuropsychobiology. 2009;60:216
- . The Naked Ape. London: Corgi Press; 1967;
- . Feelings of warmth correlate with neural activity in right anterior insular cortex. Neurosci. Lett. 2005;389:1–5
- . Human psychopharmacology of ecstasy (MDMA): a review of fifteen years of empirical research. Hum. Psychopharmacol. 2001;16:557–577
- . Recreational ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity. Pharmacol. Biochem. Behav. 2002;71:837–844
- . Is ecstasy MDMA? A review of the proportion of ecstasy tablets containing MDMA, dosage levels, and the changing perceptions of purity. Psychopharmacology. 2004;173:234–241
- . MDMA (3,4-methylenedioxymethamphetamine) or Ecstasy: the neuropsychobiological implications of taking it at dances and raves. Neuropsychobiology. 2004;50:329–335
- . Chronic tolerance to recreational MDMA (3,4-methylenedioxymethamphetamine) or Ecstasy. J. Psychopharmacol. 2005;19:71–83
- . MDMA in humans: factors which affect the neuropsychobiological profiles of recreational Ecstasy users, the integrative role of bio-energetic stress. J. Psychopharmacol. 2006;20:147–163
- . Cortisol and MDMA (3,4-methylenedioxymethamphetamine): neurohormonal aspects of bioenergetic-stress in Ecstasy users. Neuropsychobiology. 2009;60:148–158
- . Increased body temperature in recreational Ecstasy/MDMA users out clubbing and dancing. J. Psychopharmacol. 2005;19:a26
- . Dancing hot on ecstasy: physical activity and thermal comfort ratings are associated with the memory and other psychobiological problems of recreational MDMA users. Hum. Psychopharmacol. 2006;21:285–298
- . Cannabis and Ecstasy/MDMA (3,4-methylenedioxymethamphetamine): an analysis of their neuropsychobiological interactions in recreational users. J. Neural Transm. 2007;114:959–968
- . Heavy Ecstasy/MDMA use at cool house parties: substantial cortisol release and increased body temperature. J. Psychopharmacol. 2007;21:a35
- . Dance clubbing on MDMA and during abstinence from Ecstasy/MDMA: prospective neuroendocrine and psychobiological changes. Neuropsychobiology. 2008;57:165–180
- . Methylenedioxymethamphetamine (ecstasy)-related hyperthermia. J. Emerg. Med. 2005;29:451–454
- . Subjective effects of 3,4-methylenedioxymethamphetamine in recreational users. Neuropsychopharmacology. 1988;1:273–277
- . Toxin-induced hyperthermic syndromes. Med. Clin. North Am. 2005;89:1277–1296
- . Ecstasy (MDMA, MDA, MDEA, MBDB) consumption, seizures, related offences, prices, dosage levels and deaths in the UK (1994–2003). J. Psychopharmacol. 2006;20:456–463
- . The background and chemistry of MDMA. J. Psychoactive Drugs. 1986;18:291–304
- . Hypothalamic-pituitary-thyroid axis and sympathetic nervous system involvement in hyperthermia induced by 3,4-methylenedioxymethamphetamine (Ecstasy). J. Pharmacol. Exp. Ther. 2003;305:159–166
- . Roles of norepinephrine, free fatty acids, thyroid status, and skeletal muscle uncoupling protein 3 expression in sympathomimetic-induced thermogenesis. J. Pharmacol. Exp. Ther. 2007;320:274–280
- . Emergency medical assistance during a mass gathering. Eur. J. Emerg. Med. 1999;6:249–254
- . MDMA elevates core temperature in warm and cold conditions in man. In: College on Problems of Drug Dependence Annual Conference. Florida, USA, June 2003. 2003;Conference Abstract, p. 169
- . Ecstasy use in Australia: patterns of use and associated harm. Drug Alcohol Depend. 1999;55:105–115
- . Psychological and cardiovascular effects and short-term sequelae of MDMA (“ecstasy”) in MDMA-naive healthy volunteers. Neuropsychopharmacology. 1998;19:241–251
- . Amphetamine toxicity. Semin. Respir. Crit. Care Med. 2002;23:27–36
- . Saturday night fever: ecstasy related problems in a London accident and emergency department. J. Acc. Emerg. Med. 1998;15:322–326
- . Drugs and the dance music scene: a survey of current drug use patterns among a sample of dance music enthusiasts in the UK. Drug Alcohol Depend. 2001;64:9–17
PII: S0376-8716(11)00357-7
doi: 10.1016/j.drugalcdep.2011.08.012
© 2011 Elsevier Ireland Ltd. All rights reserved.
« Previous
Next »
Drug and Alcohol Dependence
Volume 121, Issue 1
, Pages 1-9
, 1 February 2012
