Opioid overdose and naloxone: The antidote to an epidemic?
References (0)
Cited by (5)
Factors associated with naloxone administration in an opioid dependent sample
2018, Journal of Substance Abuse TreatmentCitation Excerpt :Despite the continued increased availability of naloxone and national data showing that the vast majority of layperson naloxone use is administered by opioid dependent individuals (Wheeler et al., 2015), research examining demographic and clinical factors associated with naloxone administration in this population is scarce. The few existing reviews examining the efficacy of naloxone distribution programs have focused on heroin users (McDonald & Strang, 2016), perhaps because naloxone distribution organizations tend to target settings with higher presence of heroin users, IDUs, and those with a history of overdose (e.g., drug treatment programs, needle exchanges; Green & Doe-Simkins, 2016). Yet, national data from organizations distributing naloxone to laypersons report that heroin was involved in 81.6% and prescription opioids in 14.1% of reported cases of naloxone overdose reversal (Wheeler et al., 2015), thus indicating a need to better understand the role of prescription opioids in naloxone use.
A retrospective review of unintentional opioid overdose risk and mitigating factors among acutely injured trauma patients
2017, Drug and Alcohol DependenceCitation Excerpt :There are calls for increasing the availability of naloxone through provider opioid co-prescribing and dispensing at community pharmacies and other community health care and treatment settings. ( Centers for Disease Control and Prevention, 2015; Davis et al., 2014; Doyon et al., 2014; Green et al., 2015; Green and Doe-Simkins, 2016). More recent opioid prescribing guidelines for chronic pain issued by the Centers for Disease Control and Prevention (CDC, 2016) recommend prescribing naloxone if the daily dose of opioids ≥ 50 MME, or when a patient is receiving both benzodiazepines and opioid medications, or when there is a patient history of substance use disorder (SUD).
Nonprescription availability of the opioid antagonist naloxone
2018, American Journal of Health-System PharmacyFrom Peers to Lay Bystanders: Findings from a Decade of Naloxone Distribution in Pittsburgh, PA
2018, Journal of Psychoactive DrugsReversal of opioid-induced toxicity
2017, Indian Journal of Palliative Care